The efficiency of chemical reactions can be greatly enhanced over common batch processes and new approaches to the optimization of established reaction protocols and the execution of hitherto unfeasible processes can be enabled due to the inherent properties of micro/flow reactors: high mass-transfer rates, spatial separation of reagent addition and mixing, high reagent dispersion, high energy efficiency, improved irradiation, ease of upscaling, low hazard potential and multidimensional parameter control. The recent developments of microreactor technologies have significantly impacted the art of organic synthesis and manufacture. The modular home-made flow reactor can serve as a prototype model for the continuous operation of various other reactions at light/liquid/gas interfaces in student, research, and industrial laboratories. The optimized set of conditions enabled the shortening of reaction times by more than 99% with equal chemoselectivities. Major emphasis was laid on the realization of a constant and highly reproducible gas/liquid slug flow and the effective illumination by an appropriate light source. The tubular microreactor was successfully applied to the photooxygenation of hydrocarbons (Schenck ene reaction). Unlike many commercial thin-film and microchannel reactors, the described set-up operates residence times of up to 30 min which cover the typical rates of many organic reactions. This paper describes in full detail the nature and function of the required building elements, the assembly of parts, and the tuning and interdependencies of the most important reactor and reaction parameters. A home-built microreactor system for light-mediated biphasic gas/liquid reactions was assembled from simple commercial components.
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